Exercise 2: Molecular Phylogenetics of HIVs and SIVs

Answer the following questions by pressing the Edit button at the top of the tutorial window and typing your answer in the space provided. Remember to save when you have finished.

Find the HIV-1 sequences on the tree you created.


Question 1: From which African primate species did humans contract HIV-1?
> 


Question 2: How many times did this occur? Explain your answer.
> 


Question 3: How much bootstrap support is there for your conclusions?
> 


Find the HIV-2 sequences on the tree.


Question 4: From which African primate species did humans contract HIV-2?
> 


Question 5: How many times does this appear to have happened? Explain your answer.
> 


Question 6: How much bootstrap support do you have for your conclusions?
> 


Find the rhesus macaque (MAC), stump-tailed macaque (STM) and pig-tailed macaque (MNE) SIV sequences.


Question 7: From which African primate species did these Asian macaque species contract an SIV in captivity?
> 


Exercise 3: The Origin of the HIV-1 Pandemic